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Activating AMPK has broad … On IGF-1 : https://stardust.bio/article/69/igf-1-therapy-explained-all-research-and-overview, On FOXO4-DRI: https://stardust.bio/article/73/foxo4-dri-therapy-explained-all-research-and-overview, Nicotinamide Riboside ( FIXED ) : https://stardust.bio/article/74/nicotinamide-riboside-explained-all-research-and-truth, NMN: https://stardust.bio/article/76/nicotinamide-mononucleotide-nmn-explained-all-research-and-overview. It seems to do so in these two studies, funny this is the first time i've heard of that, up to 23% decrease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296448/, https://www.ncbi.nlm.nih.gov/pubmed/22607767. I have now added a feedback comment system on the website (the speech bubble on the right), for any suggested changes or corrections please post it there. to be fair, all I did was answer a question here. The purpose of my blog is not to draw general discussion away from Reddit. 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